Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287768 | 0.89 | HTR3E (0.47) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28289237 | 0.83 | F7 (0.57) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28289146 | 0.83 | KDM4E (0.68) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28872119 | 0.83 | HTR3E (0.50) | GABRA1GABRB2GABRB1GABRA3HTR3E | |
| SCHEMBL28287797 | 0.81 | HSD17B10 (0.54) | GABRA1GABRB2GABRB1GABRA3HTR3E | |
| SCHEMBL27795085 | 0.81 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL2979894 | 0.81 | KDM4E (0.68) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28287756 | 0.80 | CFTR (0.49) | GABRA1GABRB2GABRB1GABRA3HTR3E | |
| SCHEMBL28289125 | 0.80 | KDM4E (0.62) | NR4A2MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28289144 | 0.80 | KMT2A (0.55) | GABRA1GABRB2MAPTHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651247-A | A kind of green high-efficient synthetic method of carbostyril compound | 云南民族大学 | 2019-04-19 | — | — | CN | disclosed |