Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287773 | 0.86 | KDM4E (0.44) | F7F3NR4A2HTR3EHTR3B | |
| SCHEMBL28289146 | 0.83 | KDM4E (0.68) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22955936 | 0.83 | F7 (0.61) | F7F3NR4A2HTR3EHTR3B | |
| SCHEMBL28872119 | 0.83 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28289141 | 0.83 | GABRA1 (0.57) | NR4A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28287797 | 0.81 | HSD17B10 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL398364 | 0.81 | F7 (0.81) | F7F3NR4A2ALDH1A1KMT2A | |
| SCHEMBL27774061 | 0.81 | F7 (0.66) | F7F3NR4A2KDM4EHSD17B10 | |
| SCHEMBL28289125 | 0.80 | KDM4E (0.62) | NR4A2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL28289144 | 0.80 | KMT2A (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651247-A | A kind of green high-efficient synthetic method of carbostyril compound | 云南民族大学 | 2019-04-19 | — | — | CN | disclosed |