Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KDM5A | P29375 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292414 | 0.88 | P2RX7 (0.49) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL18519145 | 0.83 | P2RX7 (0.68) | CYP3A4P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL27856650 | 0.82 | P2RX7 (0.46) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL80530 | 0.79 | MPO (1.00) | MPOCYP3A4KDM5ABLMGFER | |
| Hydrochloric Acid SCHEMBL8386467 | 0.77 | MPO (0.95) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL455687 | 0.75 | KDM4E (0.59) | P2RX7ALDH1A1KDM4EMAPTLMNA | |
| Benzoic Acid Hydrazide SCHEMBL28292413 | 0.74 | ALDH1A1 (0.42) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL5480869 | 0.74 | MPO (0.87) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL1142172 | 0.73 | P2RX7 (0.74) | CYP3A4P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL5452318 | 0.73 | MPO (0.64) | MPOCYP3A4KDM5ABLMGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666047-B | Ruthenium fluorescent probe, and preparation method, application and application product thereof | 东南大学 | 2021-04-06 | — | — | CN | claimed |
| CN-109666047-B | Ruthenium fluorescent probe, and preparation method, application and application product thereof | 东南大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109666047-B | Ruthenium fluorescent probe, and preparation method, application and application product thereof | 东南大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109666047-A | A kind of ruthenium fluorescence probe and preparation method thereof, application and apply product | 东南大学 | 2019-04-23 | — | — | CN | disclosed |