Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598526 | 0.89 | NLRP3 (0.45) | ENPP2GAAMAOAABL1TAS1R3 | |
| SCHEMBL10830196 | 0.88 | ENPP2 (0.46) | ENPP2HDAC1HDAC8GAAUSP2 | |
| SCHEMBL28380843 | 0.81 | ENPP2 (0.52) | ENPP2HDAC1HDAC8GAAUSP2 | |
| SCHEMBL20656865 | 0.81 | ENPP2 (0.52) | ENPP2HDAC1HDAC8GAAUSP2 | |
| SCHEMBL25005847 | 0.76 | SLC1A3 (0.47) | KDM4EALDH1A1GLAMAOB | |
| SCHEMBL27305897 | 0.76 | ELANE (0.52) | GAAKDM4EMAPTPKMAPEX1 | |
| SCHEMBL3149877 | 0.75 | USP2 (0.50) | ENPP2HDAC1HDAC8GAAUSP2 | |
| SCHEMBL27623659 | 0.75 | MAOA (0.59) | HDAC1GAAUSP2ALOX15RAD51 | |
| SCHEMBL30621292 | 0.75 | MAOA (0.59) | HDAC1GAAUSP2ALOX15RAD51 | |
| SCHEMBL27626299 | 0.74 | USP2 (0.53) | ENPP2HDAC1HDAC8GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |