Triphenylene

Triphenylene

SCHEMBL4591073

c1ccc2c(c1)Cc1ccccc1-2.c1ccc2c(c1)c1ccccc1c1ccccc21.c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.56
KDM4E B2RXH2 2/20 0.52
NPC1 O15118 2/20 0.52
MAPT P10636 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
HPGD P15428 1/20 0.52
SRD5A2 P31213 1/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
BCHE P06276 2/20 0.46
CES1 P23141 1/20 0.46
ACHE P22303 1/20 0.44
PLK4 O00444 1/20 0.43
DAPK3 O43293 1/20 0.43
PIM1 P11309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylene SCHEMBL21360057 0.97 MAOA (0.59) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL14118022 0.91 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL28818074 0.88 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL545861 0.88 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 0.88 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29478468 0.88 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 0.88 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8180 0.88 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL1039293 0.85 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL2432881 0.85 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874892-A1 MATRIX MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICES Philips Intellectual Property & Standards GmbH (DE) 2008-01-09 EP disclosed
WO-2006111886-A1 MATRIX MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICES PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH (DE) 2006-10-26 WO disclosed