Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111186 | 0.86 | CRHBP (0.62) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL10073543 | 0.86 | KDM4E (0.63) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL28662303 | 0.84 | CYP2A13 (0.59) | MPOKDM4EALDH1A1MAPTGAA | |
| SCHEMBL3378848 | 0.84 | KDM4E (0.67) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL10415354 | 0.82 | MPO (0.84) | MPOKDM4EALDH1A1MAPTGAA | |
| SCHEMBL10665335 | 0.82 | KDM4E (0.70) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL7946364 | 0.81 | MPO (0.81) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30275949 | 0.80 | KDM4E (0.56) | MPOKDM4EALDH1A1POLBHRH3 | |
| SCHEMBL5272508 | 0.80 | KDM4E (0.55) | MPOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL3377345 | 0.80 | MPO (0.56) | MPOKDM4EALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715147-A | Anti-malarial compositions and uses thereof | 斯克利普斯研究院 | 2019-05-03 | — | — | CN | disclosed |