Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415354 | 0.98 | MPO (0.84) | MPOKDM4EHRH3ALDH1A1TSHR | |
| SCHEMBL3967782 | 0.90 | MPO (1.00) | MPOKDM4EHRH3ALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL28973467 | 0.89 | MPO (0.70) | MPOKDM4EHRH3ALDH1A1TSHR | |
| SCHEMBL11194277 | 0.85 | ALDH1A1 (0.73) | MPOKDM4EHRH3ALDH1A1TSHR | |
| SCHEMBL9388542 | 0.84 | MPO (0.88) | MPOKDM4EHRH3ALDH1A1TSHR | |
| SCHEMBL26682722 | 0.83 | MPO (0.66) | MPOKDM4EHRH3ACHELMNA | |
| SCHEMBL11196594 | 0.83 | ALDH1A1 (0.69) | MPOKDM4EHRH3ALDH1A1POLB | |
| SCHEMBL10665335 | 0.82 | KDM4E (0.70) | MPOKDM4EHRH3ALDH1A1TSHR | |
| SCHEMBL6573503 | 0.81 | HRH3 (0.96) | MPOKDM4EHRH3ALDH1A1GAA | |
| SCHEMBL28290127 | 0.81 | MPO (0.58) | MPOKDM4EHRH3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113588361-A | Isoelectric point standard substance for free flow electrophoresis | 上海蓝析生物技术有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-102395557-A | Kinase inhibitor compounds | UNIV FLORIDA | 2012-03-28 | — | — | CN | claimed |
| CN-116693469-B | Synthesis and refining method of roxatidine acetate hydrochloride | 四川汇宇制药股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-116693469-A | Synthesis and refining method of roxatidine acetate hydrochloride | 四川汇宇制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113588361-A | Isoelectric point standard substance for free flow electrophoresis | 上海蓝析生物技术有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-107857743-B | Method for preparing roxatidine acetate hydrochloride and intermediate | 北京四环制药有限公司 | 2020-08-18 | — | — | CN | disclosed |
| EP-2764052-B1 | IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW SILICONES CORP (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9328205-B2 | Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140371056-A1 | Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW COMING CORPORATION (US) | 2014-12-18 | — | — | US | disclosed |
| CN-102056933-B | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV | 2014-09-17 | — | — | CN | disclosed |
| EP-2764052-A2 | IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | Dow Corning Corporation (US) | 2014-08-13 | — | — | EP | disclosed |
| CN-1305852-C | Diaryl ethers as opioid receptor antagonists | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1681498-A | Diaryl ethers as opioid receptor antagonist | LILLY CO ELI (US) | 2005-10-12 | — | — | CN | disclosed |
| US-6262078-B1 | Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain | SYNTEX (U.S.A.) LLC | 2001-07-17 | — | — | US | disclosed |
| US-6110937-A | A SODIUM CHANNEL BLOCKER TREATING AS LOCAL ANESTHETICS AND IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | SYNTEX USA, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0869119-A1 | Phenoxymethyl piperidine derivatives being sodium channle blockers | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-07 | — | — | EP | disclosed |
| CN-1194977-A | Phenoxymethyl piperidine derivatives | HOFFMANN LA ROCHE (CH) | 1998-10-07 | — | — | CN | disclosed |
| EP-0325268-A1 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-07-26 | — | — | EP | disclosed |
| US-4124545-A | Carbamic acid esters as catalysts for trimerization of isocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |
| US-3985789-A | Carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |