Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17593254 | 0.75 | IDO1 (0.53) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL17009151 | 0.75 | PLAAT3 (0.44) | HDAC1HDAC6ALOX5PLAAT3PLAAT5 | |
| SCHEMBL28446468 | 0.75 | HDAC1 (0.72) | HDAC1HDAC6HDAC2ALOX5HDAC8 | |
| SCHEMBL28291704 | 0.72 | HDAC1 (0.58) | HDAC1HDAC6HDAC2ALOX5 | |
| SCHEMBL11637741 | 0.72 | MAPT (0.47) | HDAC1HDAC6HDAC2ALOX5HDAC8 | |
| SCHEMBL17451869 | 0.71 | POLB (0.44) | LMNAIDO1 | |
| SCHEMBL21125371 | 0.71 | KMT2A (0.43) | LMNA | |
| SCHEMBL22306511 | 0.70 | HDAC1 (0.53) | HDAC1HDAC6HDAC2ALOX5HDAC8 | |
| SCHEMBL1858237 | 0.70 | IDO1 (0.55) | HDAC1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11039172 | 0.70 | PLAAT3 (0.54) | HDAC1HDAC6HDAC2ALOX5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715615-A | Biaryl methyl heterocycles | 蒙特利尔大学 | 2019-05-03 | — | — | CN | disclosed |