Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.58 |
| ▸ | SDCBP | O00560 | 1/20 | 0.45 |
| ▸ | SDC2 | P34741 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296228 | 0.83 | CASP1 (0.54) | HDAC1KMT2AALDH1A1MEN1ALOX5 | |
| SCHEMBL5381881 | 0.78 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1GAAHDAC2 | |
| SCHEMBL3564467 | 0.78 | KMT2A (0.47) | HDAC1HDAC6SDCBPSDC2KMT2A | |
| SCHEMBL9977222 | 0.77 | HDAC1 (0.44) | HDAC1HDAC6SDCBPSDC2KMT2A | |
| SCHEMBL31589186 | 0.77 | KMT2A (0.42) | HDAC1HDAC6KMT2AMEN1 | |
| SCHEMBL8621238 | 0.75 | FAAH (0.61) | KMT2AMEN1 | |
| SCHEMBL31589279 | 0.75 | BIRC2 (0.42) | HDAC1HDAC6KMT2AALDH1A1MEN1 | |
| SCHEMBL18796564 | 0.75 | FAAH (0.61) | KMT2AMEN1 | |
| SCHEMBL8018038 | 0.75 | FAAH (0.61) | KMT2AMEN1 | |
| SCHEMBL12960584 | 0.75 | FAAH (0.61) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715615-A | Biaryl methyl heterocycles | 蒙特利尔大学 | 2019-05-03 | — | — | CN | disclosed |