Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872057 | 0.87 | L3MBTL1 (0.39) | L3MBTL1TSHRGAAMAPK1MAPT | |
| SCHEMBL29151175 | 0.80 | L3MBTL1 (0.42) | L3MBTL1TSHRGAAMAPK1MAPT | |
| SCHEMBL6307009 | 0.79 | PRKCI (0.42) | TSHRGAAMAPK1MAPTHTT | |
| SCHEMBL26640858 | 0.78 | L3MBTL1 (0.55) | L3MBTL1TSHRGAAMAPK1MAPT | |
| SCHEMBL23004816 | 0.78 | PNMT (0.41) | GAACA1CA2HTR6ALOX15 | |
| SCHEMBL26640991 | 0.77 | ADRA2B (0.42) | L3MBTL1TSHRGAAMAPK1MAPT | |
| SCHEMBL19742714 | 0.77 | CYP3A4 (0.45) | L3MBTL1TSHRGAACA1CA2 | |
| SCHEMBL13723072 | 0.77 | L3MBTL1 (0.40) | L3MBTL1GAACA1CA2PRKCI | |
| SCHEMBL19742536 | 0.76 | EPHX2 (0.40) | L3MBTL1TSHRGAAMAPTCA1 | |
| SCHEMBL28736651 | 0.74 | ALOX5AP (0.41) | L3MBTL1TSHRGAAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |