Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290537 | 0.81 | ALDH1A1 (0.46) | KMT2AHTTLMNASMN1; SMN2GAA | |
| SCHEMBL16960064 | 0.81 | MAPT (0.44) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL28290498 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL8609293 | 0.75 | MAPT (0.51) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL17593420 | 0.75 | CYP19A1 (0.51) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL4043515 | 0.75 | CYP19A1 (0.55) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL2086886 | 0.75 | CYP19A1 (0.55) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL16959982 | 0.74 | MAPT (0.48) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL1470776 | 0.74 | ALDH1A1 (0.55) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL16956126 | 0.74 | MEN1 (0.44) | MAPTMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |