Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290498 | 0.82 | MAPT (0.47) | ALDH1A1HIF1AGAAHTTTHRB | |
| SCHEMBL28290421 | 0.81 | MAPT (0.41) | ALDH1A1GAAHTTTDP1LMNA | |
| SCHEMBL3641932 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HIF1AGAAHTTTHRB | |
| SCHEMBL31506366 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HIF1AGAAHTTTHRB | |
| SCHEMBL16960112 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HIF1AGAAHTTTHRB | |
| SCHEMBL5693765 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HIF1AGAAHTTTHRB | |
| SCHEMBL1030342 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HIF1AGAATDP1TSHR | |
| SCHEMBL29744802 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HIF1AGAATDP1TSHR | |
| SCHEMBL17106594 | 0.74 | MAPT (0.45) | ALDH1A1GAAL3MBTL1TDP1TSHR | |
| SCHEMBL28290413 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GAAHTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |