Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339129 | 0.86 | DYRK1A (0.61) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 | |
| Hydrochloric Acid SCHEMBL8556369 | 0.83 | DYRK1A (0.58) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 | |
| Hydrochloric Acid SCHEMBL8556367 | 0.83 | DYRK1A (0.58) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 | |
| SCHEMBL3716710 | 0.80 | GSK3B (0.48) | ALDH1A1GPR183DYRK1AERN1MAPT | |
| SCHEMBL29845506 | 0.80 | GSK3B (0.48) | ALDH1A1GPR183DYRK1AERN1MAPT | |
| Anisaldehyde SCHEMBL6846902 | 0.79 | ALDH1A1 (0.58) | ALDH1A1CYP2A6MAPTRAB9AMEN1 | |
| Piperonal SCHEMBL20184609 | 0.78 | ALDH1A1 (0.72) | ALDH1A1CYP2A6DYRK1ADYRK1BDYRK2 | |
| SCHEMBL30679660 | 0.77 | ERN1 (0.64) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 | |
| SCHEMBL29957044 | 0.77 | DYRK1A (0.61) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 | |
| SCHEMBL3328614 | 0.77 | DYRK1A (0.61) | ALDH1A1DYRK1ADYRK1BDYRK2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |