Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.61 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.61 |
| ▸ | CLK1 | P49759 | 4/20 | 0.61 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.46 |
| ▸ | WNT3A | P56704 | 6/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328614 | 1.00 | DYRK1A (0.61) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| SCHEMBL3517912 | 0.95 | DYRK1A (0.56) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| SCHEMBL339129 | 0.89 | DYRK1A (0.61) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| SCHEMBL3327121 | 0.86 | ALDH1A1 (0.50) | DYRK1ADYRK1BCLK1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8556369 | 0.86 | DYRK1A (0.58) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8556367 | 0.86 | DYRK1A (0.58) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| SCHEMBL18586105 | 0.83 | DYRK1A (0.56) | DYRK1ADYRK1BCLK1DYRK2CTNNB1 | |
| SCHEMBL18586107 | 0.83 | DYRK1A (0.56) | DYRK1ADYRK1BCLK1DYRK2CTNNB1 | |
| SCHEMBL15853567 | 0.83 | DYRK1A (0.46) | DYRK1ADYRK1BCLK1DYRK2ALDH1A1 | |
| SCHEMBL2142665 | 0.82 | DYRK1A (0.57) | DYRK1ADYRK1BCLK1DYRK2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | DYRK1A 693/4885DYRK1B 1343/4885CLK1 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.