SCHEMBL339129

SCHEMBL339129

O=Cc1ccc2c(c1)CCO2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 11/20 0.61
DYRK1B Q9Y463 10/20 0.61
DYRK2 Q92630 7/20 0.61
ERN1 O75460 3/20 0.54
ALDH1A1 P00352 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CLK1 P49759 6/20 0.53
CLK2 P49760 4/20 0.51
CLK3 P49761 2/20 0.51
CSNK2A2 P19784 2/20 0.51
CSNK2B P67870 2/20 0.51
CSNK2A1 P68400 2/20 0.51
PIK3CA P42336 1/20 0.51
PRKCI P41743 1/20 0.47
DYRK3 O43781 4/20 0.44
CLK4 Q9HAZ1 3/20 0.44
DYRK4 Q9NR20 3/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8556367 0.96 DYRK1A (0.58) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
Hydrochloric Acid SCHEMBL8556369 0.96 DYRK1A (0.58) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL3328614 0.89 DYRK1A (0.61) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL29957044 0.89 DYRK1A (0.61) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL3517912 0.87 DYRK1A (0.56) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
Anisaldehyde SCHEMBL28290436 0.86 ALDH1A1 (0.54) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL30679660 0.86 ERN1 (0.64) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL2416319 0.85 ALDH1A1 (0.53) DYRK1ADYRK1BDYRK2ERN1ALDH1A1
SCHEMBL1647020 0.82 DYRK1A (0.55) DYRK1ADYRK1BDYRK2ERN1CLK1
SCHEMBL29585187 0.82 DYRK1A (0.55) DYRK1ADYRK1BDYRK2ERN1CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
CN-114656455-B Triazole modified ferric oxide photocatalyst and preparation method thereof 常熟华虞环境科技有限公司 2022-08-09 CN claimed
CN-114656455-A Triazole modified ferric oxide photocatalyst and preparation method thereof 常熟华虞环境科技有限公司 2022-06-24 CN claimed
WO-2010041271-A2 PROCESS FOR PREPARATION OF (S)-N-[2-(1,6,7,8-TETRAHYDRO-2H-INDENO[5,4-B]FURAN-8-YL)ETHYL] PROPIONAMIDE AND NOVEL INTERMEDIATES THEREOF USV LIMITED (IN) 2010-04-15 WO claimed
EP-1891034-A2 PROCESSES FOR PREPARING DARIFENACIN HYDROBROMIDE Teva Pharmaceutical Fine Chemicals S.R.L. (IT) 2008-02-27 EP claimed
US-20070197631-A1 Processes for preparing darifenacin hydrobromide TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-08-23 US claimed
WO-2007076157-A2 PROCESSES FOR PREPARING DARIFENACIN HYDROBROMIDE TEVA PHARMACEUTICALS INDUSTRIES LTD. (IL) 2007-07-05 WO claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
EP-1292268-B1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KGAA (DE) 2005-02-23 EP claimed
EP-1292269-B1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KGAA (DE) 2005-02-09 EP claimed
US-6790239-B1 COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-14 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
EP-1292269-A1 AGENT FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-1235549-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-04 EP claimed
WO-2001097765-A1 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001034106-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 DYRK1A 2614/4885DYRK1B 2366/4885DYRK2 2511/4885
US-20070197631-A1 Processes for preparing darifenacin hydrobromide OPRL1, AVPR2, AVPR1B DYRK1A 1395/4885DYRK1B 1310/4885DYRK2 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.