Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539724 | 0.80 | TSHR (0.54) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL30405501 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL6307182 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL2401756 | 0.77 | TSHR (0.41) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL14301697 | 0.77 | KMT2A (0.42) | TSHRALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL19814248 | 0.76 | CDK2 (0.49) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL2372426 | 0.74 | ALDH1A1 (0.40) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL30769656 | 0.74 | ALDH1A1 (0.40) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL14868671 | 0.74 | HSP90AA1 (0.41) | TSHRALDH1A1LMNAHTTMAPT | |
| SCHEMBL2401652 | 0.74 | CA1 (0.38) | TSHRALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |