Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28060489 | 0.85 | TDP1 (0.45) | TDP1HPGDCA2CA12CA1 | |
| SCHEMBL10683 | 0.84 | CA2 (0.48) | HPGDCA2CA12CA1CA9 | |
| Tert-Butyl Formate SCHEMBL27722072 | 0.83 | TDP1 (0.43) | TDP1HPGDCA2CA12CA1 | |
| Hydrochloric Acid SCHEMBL3180234 | 0.82 | HPGD (0.47) | HPGDCA2CA12CA1CA9 | |
| Tert-Butyl Formate SCHEMBL27838561 | 0.81 | TDP1 (0.41) | TDP1HPGDCA2CA12CA1 | |
| Tert-Butyl Formate SCHEMBL28060441 | 0.81 | TDP1 (0.41) | TDP1HPGDCA2CA12CA1 | |
| Tert-Butyl Formate SCHEMBL27836174 | 0.81 | TPSAB1 (0.42) | TDP1HPGDCA2CA12CA1 | |
| Tert-Butyl Formate SCHEMBL28827129 | 0.81 | POLB (0.46) | TDP1HPGDCA2CA12CA1 | |
| Tert-Butyl Formate SCHEMBL27838577 | 0.80 | CHRNB2 (0.64) | TDP1HPGDMEN1KMT2ACHRNB2 | |
| Tert-Butyl Formate SCHEMBL27878208 | 0.79 | TDP1 (0.50) | TDP1HPGDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |