Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107197 | 0.83 | CES2 (0.52) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL28904670 | 0.77 | CES2 (0.51) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL28290498 | 0.77 | MAPT (0.47) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL27432755 | 0.76 | LMNA (0.50) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL11010668 | 0.75 | LMNA (0.60) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL5313439 | 0.75 | MAPT (0.60) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL27741625 | 0.75 | MAPT (0.55) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL27604697 | 0.74 | CES2 (0.54) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL28290537 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAHTTPOLB | |
| Methylamine SCHEMBL28159482 | 0.74 | ALDH1A1 (0.65) | ALDH1A1LMNAGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |