Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289352 | 0.88 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28290817 | 0.87 | GRIN2B (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1789154 | 0.84 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3233695 | 0.80 | HPGD (0.65) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL16767423 | 0.80 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8857021 | 0.78 | HPGD (0.63) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL19357342 | 0.78 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21656854 | 0.78 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14220967 | 0.77 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4003420 | 0.77 | CA12 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003104-A | Salicyclic acid derivatives, its pharmaceutically acceptable salt, its composition and its application method | 多伦多大学管理委员会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105120854-B | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | 多伦多大学管理委员会 | 2019-04-09 | — | — | CN | disclosed |