Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290801 | 0.88 | RAB9A (0.53) | RAB9AKMT2AGAAALDH1A1MAPT | |
| SCHEMBL28290817 | 0.85 | GRIN2B (0.52) | RAB9AKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL6425991 | 0.85 | KMT2A (0.69) | RAB9AKMT2AGAALMNASLC6A2 | |
| SCHEMBL15534528 | 0.84 | HSP90AA1 (0.54) | RAB9AKMT2AGAALMNASLC6A2 | |
| SCHEMBL4049737 | 0.82 | KMT2A (0.61) | RAB9AKMT2ALMNASLC6A2SLC6A3 | |
| SCHEMBL28289348 | 0.82 | SGMS2 (0.47) | KMT2ALMNAALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL28289353 | 0.82 | SGMS2 (0.44) | RAB9AKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20400908 | 0.77 | HSP90AA1 (0.48) | RAB9AKMT2AGAALMNASLC6A2 | |
| SCHEMBL16766373 | 0.76 | STAT3 (0.46) | RAB9AKMT2ALMNASLC6A2SLC6A3 | |
| SCHEMBL15984671 | 0.75 | KMT2A (0.58) | RAB9AKMT2AGAALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003104-A | Salicyclic acid derivatives, its pharmaceutically acceptable salt, its composition and its application method | 多伦多大学管理委员会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105120854-B | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | 多伦多大学管理委员会 | 2019-04-09 | — | — | CN | disclosed |