Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL2488792 | 0.97 | — | — | |
| SCHEMBL465616 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL11247031 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL8012629 | 0.90 | — | — | |
| SCHEMBL8981852 | 0.90 | — | — | |
| Butadiene SCHEMBL10734664 | 0.88 | LMNA (0.44) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acrylic Acid SCHEMBL2942899 | 0.88 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Acetic Acid SCHEMBL8893677 | 0.85 | ALDH1A1 (0.47) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| Vinyl Chloride SCHEMBL27606793 | 0.85 | LMNA (0.42) | LMNAALOX15HSD17B10ALDH1A1TSHR | |
| SCHEMBL28369427 | 0.80 | ALDH1A1 (0.43) | LMNAALOX15HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790399-A | Coalescent and nonionic surfactant blend | 伊士曼化工公司 | 2019-05-21 | — | — | CN | disclosed |