Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465616 | 0.91 | — | — | |
| SCHEMBL8981852 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL11247031 | 0.88 | — | — | |
| Ethylene SCHEMBL2488792 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8012629 | 0.88 | — | — | |
| Butadiene SCHEMBL10734664 | 0.85 | LMNA (0.44) | ALDH1A1TSHRTP53LMNAALOX15 | |
| Acrylic Acid SCHEMBL2942899 | 0.85 | LMNA (0.62) | ALDH1A1TSHRTP53LMNAALOX15 | |
| Bicarbonate SCHEMBL28290875 | 0.85 | LMNA (0.44) | ALDH1A1TSHRTP53LMNAALOX15 | |
| Vinyl Chloride SCHEMBL27606793 | 0.82 | LMNA (0.42) | ALDH1A1TSHRLMNAALOX15HSD17B10 | |
| SCHEMBL28369427 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174170-B2 | Method for producing liquid high-purity polyhydric alcohol derivative-modified silicone or composition thereof | DOW CORNING TORAY CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170218130-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY POLYHYDRIC ALCOHOL DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | DOW TORAY CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-3147307-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY POLYHYDRIC ALCOHOL DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | Dow Corning Toray Co., Ltd. (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-5672561-A | RIBBON SUBSTRATE COATED WITH INK LAYER AREAS AND SEPARATELY DISPOSED RELEASING LAMINATE LAYER AREAS; HEAT RESISTANCE, UNIFORM TRANSFER | SONY CORPORATION (JP) | 1997-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174170-B2 | Method for producing liquid high-purity polyhydric alcohol derivative-modified silicone or composition thereof | SAMM50, SORD, ADH1C | ALDH1A1 945/4885TSHR 3860/4885TP53 633/4885 |
| US-20170218130-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY POLYHYDRIC ALCOHOL DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | SAMM50, SORD, ADH1C | ALDH1A1 945/4885TSHR 3860/4885TP53 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.