SCHEMBL28290987

SCHEMBL28290987

CCCC[Si](CCCC)(CCCC)OS(=O)(=O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CNR2 P34972 1/20 0.39
GRM2 Q14416 1/20 0.38
LTA4H P09960 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
F2 P00734 1/20 0.36
MAPT P10636 1/20 0.36
VDR P11473 1/20 0.36
CA4 P22748 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.35
PLA2G10 O15496 1/20 0.35
PLA2G2A P14555 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057574 0.88 TDP1 (0.45) ALDH1A1KDM4EMAPTTDP1
SCHEMBL2057589 0.85 CA2 (0.44) CA2CA12CA1CA9SMN1; SMN2
SCHEMBL2058003 0.82 ABCB1 (0.44) CA2CA12CA1CA9ALDH1A1
SCHEMBL2057910 0.79 CA2 (0.42) CA2SMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL28357583 0.79 CA2 (0.38) CA2CA12CA1CA9CA14
SCHEMBL28807218 0.79 CA1 (0.49) CA2CA12CA1CA9CA14
SCHEMBL2058178 0.78 PSIP1 (0.45) SMN1; SMN2ALDH1A1HPGDKDM4EMAPT
SCHEMBL2058025 0.75 CA2 (0.47) CA2SMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL2057507 0.75 ALDH1A1 (0.48) CA2ALDH1A1KDM4EF2MAPT
SCHEMBL2058177 0.74 TDP1 (0.44) SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111886289-B Masterbatch with semi-crystalline polyolefin carrier resin 陶氏环球技术有限责任公司 2024-12-06 CN disclosed
CN-116003896-A Radiation curable polyolefin formulations 陶氏环球技术有限责任公司 2023-04-25 CN disclosed
CN-109890877-A Additive masterbatch composition based on semicrystalline polyolefins 陶氏环球技术有限责任公司 2019-06-14 CN disclosed
CN-109790300-A Semicrystalline polyolefins based additive concentrate composition 陶氏环球技术有限责任公司 2019-05-21 CN disclosed
CN-109689758-A Moisture-curable polyolefin composition 陶氏环球技术有限责任公司 2019-04-26 CN disclosed