Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18227698 | 0.94 | PNMT (0.43) | ASIC3HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL26963045 | 0.92 | HRH3 (0.47) | ASIC3HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL30658395 | 0.88 | ASIC3 (0.44) | ASIC3HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL26963061 | 0.88 | ASIC3 (0.44) | ASIC3HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL22860678 | 0.83 | HTR2C (0.46) | HTR2CHTR2BHTR2AHRH3CYP2D6 | |
| SCHEMBL29501433 | 0.81 | SLC18A3 (0.50) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL28587390 | 0.78 | CARM1 (0.41) | ASIC3HRH3HSD17B3CARM1NOS3 | |
| SCHEMBL4573212 | 0.77 | CARM1 (0.42) | HRH3PNMTHSD17B3CARM1ABHD6 | |
| SCHEMBL29041981 | 0.77 | PRMT5 (0.39) | ASIC3HRH3HSD17B3CARM1ABHD6 | |
| SCHEMBL13139628 | 0.76 | HRH3 (0.39) | HTR2CHTR2BHRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810111-B | Pyrazolopyrimidine compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-109810111-A | A kind of pyrazolone miazines compound, preparation method and application | 上海医药集团股份有限公司 | 2019-05-28 | — | — | CN | disclosed |