SCHEMBL28291100

SCHEMBL28291100

C=CC[O].O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.41
P2RX7 Q99572 1/20 0.37
ALDH1A1 P00352 5/20 0.36
HTT P42858 5/20 0.36
MAPT P10636 5/20 0.36
MITF O75030 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
FGFR1 P11362 2/20 0.36
FGFR2 P21802 2/20 0.36
FGFR4 P22455 2/20 0.36
FGFR3 P22607 2/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
GAA P10253 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
PLA2G10 O15496 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 4/20 0.35
CDC25A P30304 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292552 0.85 PDE4B (0.45) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL516326 0.82 PDE4B (0.54) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL4250744 0.79 PDE4B (0.52) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL13170491 0.79 PDE4B (0.52) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL20160837 0.79 PDE4B (0.52) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL13170578 0.79 PDE4B (0.52) PDE4BP2RX7ALDH1A1HTTMAPT
Ethyne SCHEMBL28292549 0.77 PDE4B (0.50) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL20160807 0.77 LMNA (0.52) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL7192214 0.75 PDE4B (0.48) PDE4BP2RX7ALDH1A1HTTMAPT
SCHEMBL8693759 0.74 PDE4B (0.52) PDE4BP2RX7ALDH1A1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109749000-A Low temperature curable addition polymers from vinyl aryl cyclobutene-containing monomers and methods for making the same 罗门哈斯电子材料有限责任公司 2019-05-14 CN disclosed
CN-109651564-A From the polymer and preparation method for passing through the cured monomer containing double arylcyclobutene groups of other groups 罗门哈斯电子材料有限责任公司 2019-04-19 CN disclosed