Ethyne

Ethyne

SCHEMBL28292549

C#C.O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.50
P2RX7 Q99572 1/20 0.45
MAPT P10636 5/20 0.43
LMNA P02545 5/20 0.43
HTT P42858 4/20 0.43
NPSR1 Q6W5P4 4/20 0.43
ALDH1A1 P00352 3/20 0.43
FGFR1 P11362 2/20 0.43
FGFR2 P21802 2/20 0.43
FGFR4 P22455 2/20 0.43
FGFR3 P22607 2/20 0.43
MITF O75030 1/20 0.43
KMT2A Q03164 4/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
BACE1 P56817 1/20 0.42
CDC25A P30304 1/20 0.42
CDC25B P30305 1/20 0.42
MEN1 O00255 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL516326 0.94 PDE4B (0.54) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL13170491 0.92 PDE4B (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL4250744 0.92 PDE4B (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL20160837 0.92 PDE4B (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL13170578 0.92 PDE4B (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL20160807 0.89 LMNA (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL7192214 0.86 PDE4B (0.48) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL8693759 0.86 PDE4B (0.52) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL16735433 0.84 FGFR1 (0.55) PDE4BP2RX7MAPTLMNAHTT
SCHEMBL16735427 0.84 FGFR1 (0.55) PDE4BP2RX7MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651564-A From the polymer and preparation method for passing through the cured monomer containing double arylcyclobutene groups of other groups 罗门哈斯电子材料有限责任公司 2019-04-19 CN disclosed