SCHEMBL28291159

SCHEMBL28291159

COc1c(OC)c(OC)c(C(O)(OC)c2ccccc2)c(OC)c1OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.38
CES1 P23141 1/20 0.38
KCNN4 O15554 1/20 0.37
MAPK1 P28482 3/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALOX15 P16050 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
CYP3A4 P08684 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.34
ACSS2 Q9NR19 2/20 0.34
MEN1 O00255 1/20 0.34
KIF11 P52732 1/20 0.33
KCNH2 Q12809 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28117527 0.81 CES1 (0.47) CA4CES1KCNN4MAPK1ALDH1A1
SCHEMBL23306705 0.80 ACSS2 (0.41) CA4CES1KCNN4MAPK1ALDH1A1
SCHEMBL18280520 0.76 CA4 (0.52) CA4CES1SMN1; SMN2KMT2AMEN1
SCHEMBL18550496 0.74 NFE2L2 (0.41) CA4ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL238442 0.72 ALDH1A1 (0.43) CA4CES1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL1279578 0.70 ALDH1A1 (0.50) CES1KCNN4MAPK1ALDH1A1ALOX15
SCHEMBL5914847 0.69 MAPK1 (0.39) CA4CES1KCNN4MAPK1ALDH1A1
SCHEMBL4372562 0.68 CES1 (0.47) CA4CES1KCNN4MAPK1ALDH1A1
SCHEMBL319709 0.68 CES1 (0.47) CES1KCNN4MAPK1ALDH1A1SMN1; SMN2
SCHEMBL28557443 0.67 ALDH1A1 (0.46) CES1KCNN4MAPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109731454-A Visualize formaldehyde scavenger and preparation method thereof 嘉兴宇鸣科技有限公司 2019-05-10 CN disclosed