SCHEMBL28291161

SCHEMBL28291161

COc1ccc(OC(=O)C(C)N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.48
CA1 P00915 5/20 0.48
CA2 P00918 5/20 0.48
PARP10 Q53GL7 2/20 0.48
PARP1 P09874 1/20 0.48
PARP2 Q9UGN5 1/20 0.48
PARP4 Q9UKK3 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
SLC6A4 P31645 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
LMNA P02545 1/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199570 1.00 ELANE (0.48) ELANECA1CA2PARP10PARP1
SCHEMBL15679080 0.92 ELANE (0.55) ELANEPARP10CYP1A2CYP2C9CYP2C19
SCHEMBL23493150 0.92 ELANE (0.55) ELANEPARP10CYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL30184762 0.90 ELANE (0.53) ELANEPARP10CYP1A2CYP2C9CYP2C19
SCHEMBL28774781 0.85 ELANE (0.46) ELANECA1CA2PARP10PARP1
SCHEMBL28774783 0.85 ELANE (0.46) ELANECA1CA2PARP10PARP1
SCHEMBL15679089 0.84 ELANE (0.48) ELANECA1CA2PARP10CA12
SCHEMBL2402636 0.84 ELANE (0.48) ELANECA1CA2PARP10CA12
SCHEMBL5058438 0.84 LMNA (0.55) ELANECYP1A2CYP2C9CYP2C19LMNA
SCHEMBL239299 0.84 ELANE (0.48) ELANEPARP10CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574906-A A kind of preparation method of 3,3 '-two Indoleacetic esters 兰州大学 2019-04-05 CN disclosed