SCHEMBL5058438

SCHEMBL5058438

Cc1ccc(OC(=O)[C@H](C)N)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
ELANE P08246 2/20 0.48
ALDH1A1 P00352 1/20 0.44
PRSS1 P07477 1/20 0.42
ACR P10323 1/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27498354 1.00 LMNA (0.55) LMNAELANEALDH1A1PRSS1ACR
SCHEMBL15679080 0.92 ELANE (0.55) LMNAELANEALDH1A1MAPTKMT2A
SCHEMBL23493150 0.92 ELANE (0.55) LMNAELANEALDH1A1MAPTKMT2A
Hydrochloric Acid SCHEMBL30184762 0.90 ELANE (0.53) LMNAELANEALDH1A1MAPTKMT2A
SCHEMBL18295352 0.85 LMNA (0.52) LMNAELANEALDH1A1PRSS1ACR
SCHEMBL26824432 0.85 LMNA (0.52) LMNAELANEALDH1A1PRSS1ACR
SCHEMBL3199570 0.84 ELANE (0.48) LMNAELANEALDH1A1GAACYP1A2
SCHEMBL15679089 0.84 ELANE (0.48) ELANEGAAMAPTKMT2AMEN1
SCHEMBL28291161 0.84 ELANE (0.48) LMNAELANEALDH1A1GAACYP1A2
SCHEMBL2402636 0.84 ELANE (0.48) ELANEGAAMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636975-A Anti-inflammatory tripeptides DR AUGUST WOLFF GMBH & CO KG ARZNEIMITTEL 2016-06-01 CN claimed
CN-113396218-B Engineered transaminase polypeptides 科德克希思公司 2025-02-18 CN disclosed
CN-118812647-A Novel insect short neuropeptide sNPF analogue and application thereof 四川轻化工大学 2024-10-22 CN disclosed
EP-4136102-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE I2O Therapeutics, Inc. (US) 2023-02-22 EP disclosed
WO-2021212023-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE INTARCIA THERAPEUTICS, INC. (US) 2021-10-21 WO disclosed
CN-110520147-A For treating the composition and method of iron overload LA JOLLA PHARMA CO 2019-11-29 CN disclosed
CN-110392685-A Selective sulfonation of benzodiazepine derivatives 伊缪诺金公司 2019-10-29 CN disclosed
CN-110312521-A Method of administering hepcidin 拉卓拉药物公司 2019-10-08 CN disclosed
CN-110267971-A Immunomodulator 百时美施贵宝公司 2019-09-20 CN disclosed
CN-105636975-B Anti-inflammatory tripeptides 奥古斯特沃尔夫博士有限两合公司-医药 2019-06-25 CN disclosed
CN-1582149-A Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels PROBIODRUG AG (DE) 2005-02-16 CN disclosed
CN-1460023-A Polymer modified bioactive synthetic chemokines and methods of production and use GRYPHON TREAT CO (US) 2003-12-03 CN disclosed
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same NOVASPIN BIOTECH GMBH (DE) 2003-06-19 US disclosed
CN-1407856-A Method of improving dough and bread quality DANISCO (DK) 2003-04-02 CN disclosed
WO-2002100885-A2 A PENTA- OR TETRAPEPTIDE BINDING TO SOMATOSTATIN RECEPTORS AND THE USE OF THE SAME NOVASPIN BIOTECH GMBH (DE) 2002-12-19 WO disclosed
EP-0721468-B1 PLATELET AGGREGATION INHIBITORY PEPTIDES NIPPON STEEL CORP (JP) 2001-05-30 EP disclosed
US-5721213-A Peptides, active as inhibitors of platelet aggregation NIPPON STEEL CORPORATION (JP) 1998-02-24 US disclosed
EP-0721468-A1 NOVEL PEPTIDE, ACTIVE AS INHIBITORS OF PLATELET AGGREGATION NIPPON STEEL CORPORATION (JP) 1996-07-17 EP disclosed
WO-1995009185-A1 NOVEL PEPTIDE, ACTIVE AS INHIBITORS OF PLATELET AGGREGATION NIPPON STEEL CORPORATION (JP) 1995-04-06 WO disclosed
EP-0331404-A2 Method for producing tropane alkaloid SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same SSTR5, SSTR3, SCTR LMNA 2982/4885ELANE 302/4885ALDH1A1 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.