Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.77 |
| ▸ | RAB9A | P51151 | 14/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.77 |
| ▸ | MAPT | P10636 | 12/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MEN1 | O00255 | 7/20 | 0.77 |
| ▸ | HPGD | P15428 | 7/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.77 |
| ▸ | GLA | P06280 | 2/20 | 0.77 |
| ▸ | GFER | P55789 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296291 | 0.94 | NPC1 (0.75) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL16424489 | 0.94 | NPC1 (0.75) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL2268609 | 0.89 | NPC1 (0.78) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL29363950 | 0.89 | NPC1 (0.78) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL28292707 | 0.89 | RAB9A (0.96) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL2245075 | 0.87 | RAB9A (1.00) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL27001624 | 0.86 | NPC1 (0.73) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL27001620 | 0.86 | NPC1 (0.73) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL28728235 | 0.86 | NPC1 (0.73) | NPC1RAB9AKDM4EMAPTALDH1A1 | |
| SCHEMBL2491134 | 0.85 | RAB9A (0.96) | NPC1RAB9AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734908-B | Polyamide acid and preparation method thereof, polyimide and preparation method of polyimide film | 武汉柔显科技股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-109734908-A | The preparation method of polyamic acid and preparation method, polyimides and Kapton | 武汉柔显科技股份有限公司 | 2019-05-10 | — | — | CN | disclosed |