SCHEMBL28291362

SCHEMBL28291362

C=Cc1ccc(-c2cc(C(=O)O)nc(C(=O)O)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 11/20 0.50
ALOX15 P16050 2/20 0.44
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC2 Q92769 1/20 0.40
SCN9A Q15858 1/20 0.40
ALDH1A1 P00352 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521089 0.88 MCL1 (0.45) MCL1KDM4EHDAC2SCN9AALDH1A1
SCHEMBL22228652 0.87 TSHR (0.48) MCL1ALOX15TSHRHIF1AKDM4E
SCHEMBL20876169 0.81 ALOX15 (0.54) MCL1ALOX15TSHRHIF1AKDM4E
SCHEMBL28521087 0.80 MAPT (0.39) MCL1KDM4EHDAC2ALDH1A1PTGS2
SCHEMBL6509907 0.78 ALOX15 (0.67) MCL1ALOX15TSHRHIF1AKDM4E
SCHEMBL17595151 0.77 MCL1 (0.56) MCL1ALOX15TSHRHIF1AKDM4E
SCHEMBL31401885 0.77 TSHR (0.61) MCL1ALOX15TSHRHIF1ASCN9A
SCHEMBL1759786 0.77 MCL1 (0.64) MCL1ALOX15TSHRHIF1AKDM4E
SCHEMBL21044577 0.76 MCL1 (0.69) MCL1ALOX15TSHRHIF1AALDH1A1
SCHEMBL17594949 0.76 SCN9A (0.56) MCL1ALOX15TSHRHIF1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796585-A A method of using the water-soluble nano material of three arm cross-linking methods preparation green light 陕西科技大学 2019-05-24 CN claimed
CN-109796585-A A method of using the water-soluble nano material of three arm cross-linking methods preparation green light 陕西科技大学 2019-05-24 CN disclosed