SCHEMBL1759786

SCHEMBL1759786

O=C(O)c1cc(-c2ccccc2)cc(C(=O)O)n1

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 9/20 0.64
ALOX15 P16050 2/20 0.56
TSHR P16473 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ACMSD Q8TDX5 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
HIF1A Q16665 1/20 0.54
ALDH1A1 P00352 1/20 0.52
KMO O15229 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14580625 0.90 MCL1 (0.73) MCL1KMO
SCHEMBL6509907 0.88 ALOX15 (0.67) MCL1ALOX15TSHRKDM4EACMSD
SCHEMBL316446 0.88 MCL1 (0.81) MCL1KMO
SCHEMBL316550 0.86 MCL1 (0.55) MCL1ALOX15TSHRKDM4EACMSD
SCHEMBL28288409 0.86 MCL1 (0.52) MCL1ALOX15KDM4EALDH1A1
SCHEMBL28135830 0.85 MCL1 (0.54) MCL1ALOX15TSHRKDM4EACMSD
Dipicolinic Acid SCHEMBL23071472 0.84 KDM4E (0.81) MCL1ALOX15TSHRKDM4EACMSD
SCHEMBL8755632 0.83 MCL1 (0.65) MCL1KMO
SCHEMBL8542300 0.83 ALDH1A1 (0.53) MCL1TSHRKDM4EALDH1A1
SCHEMBL17595151 0.83 MCL1 (0.56) MCL1ALOX15TSHRKDM4EACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN claimed
CN-118878806-A Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2024-11-01 CN claimed
CN-118781906-A Anti-counterfeiting label material and preparation method thereof 浙江赫宇包装科技有限公司 2024-10-15 CN claimed
EP-3191451-B1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) 2019-06-05 EP claimed
US-20170217889-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2017-08-03 US claimed
EP-3191451-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME Okinawa Institute of Science and Technology School Corporation (JP) 2017-07-19 EP claimed
WO-2016038890-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2016-03-17 WO claimed
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN disclosed
CN-118878808-B Composite catalyst containing zinc pyridine carboxylate complex and preparation method and application thereof 合肥普力先进材料科技有限公司 2024-12-24 CN disclosed
CN-118878808-A Composite catalyst containing zinc pyridine carboxylate complex and preparation method and application thereof 合肥普力先进材料科技有限公司 2024-11-01 CN disclosed
CN-118878806-A Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2024-11-01 CN disclosed
CN-118781906-A Anti-counterfeiting label material and preparation method thereof 浙江赫宇包装科技有限公司 2024-10-15 CN disclosed
EP-2499691-A1 METHOD FOR MECHANICALLY STABILIZING NITROGEN-CONTAINING POLYMERS BASF SE (DE) 2012-09-19 EP disclosed
EP-0525825-A2 Substituted dicarboxy pyridine compounds Dade MicroScan Inc. (US) 1993-02-03 EP disclosed
US-4925804-A REPORTER MECHANISM FOR BIOSPECIFIC REACTIONS BAXTER INTERNATIONAL INC. (US) 1990-05-15 US disclosed
EP-0272320-A4 HOMOGENEOUS FLUOROASSAY METHODS EMPLOYING FLUORESCENT BACKGROUND REJECTION. BAXTER TRAVENOL LAB (US) 1989-08-09 EP disclosed
US-4761481-A FLUORESCENT CHELATES, AMINE ACID COMPOUNDS BAXTER TRAVENOL LABORATORIES, INC. (US) 1988-08-02 US disclosed
EP-0272320-A1 HOMOGENEOUS FLUOROASSAY METHODS EMPLOYING FLUORESCENT BACKGROUND REJECTION. BAXTER TRAVENOL LAB (US) 1988-06-29 EP disclosed
WO-1987007955-A1 HOMOGENEOUS FLUOROASSAY METHODS EMPLOYING FLUORESCENT BACKGROUND REJECTION AND WATER-SOLUBLE RARE EARTH METAL CHELATE FLUOROPHORES BAXTER TRAVENOL LABORATORIES, INC. (US) 1987-12-30 WO disclosed
EP-0195413-A2 Substituted pyridine derivatives Baxter Diagnostics Inc. (US) 1986-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217889-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME PDK2, PKD1, PDHA2 MCL1 1099/4885ALOX15 1973/4885TSHR 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.