Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527133 | 0.91 | CASP1 (0.43) | CASP1TYRCTSKTACR1IDO1 | |
| SCHEMBL28472712 | 0.90 | FOLH1 (0.45) | CASP1ENPP2HDAC1HDAC2 | |
| SCHEMBL2549268 | 0.89 | PNMT (0.43) | CASP1TYR | |
| SCHEMBL2549264 | 0.89 | PNMT (0.43) | CASP1TYR | |
| SCHEMBL29897120 | 0.88 | PNMT (0.42) | CASP1 | |
| SCHEMBL30758311 | 0.85 | TYR (0.49) | TYRCTSKTACR1CTSLCTSB | |
| SCHEMBL22804041 | 0.85 | TYR (0.49) | TYRCTSKTACR1CTSLCTSB | |
| SCHEMBL8579351 | 0.85 | TYR (0.49) | TYRCTSKTACR1CTSLCTSB | |
| SCHEMBL8579349 | 0.85 | TYR (0.49) | TYRCTSKTACR1CTSLCTSB | |
| SCHEMBL3279498 | 0.84 | PNMT (0.39) | CTSKTACR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479933-A | Preparation method of N-fluorenylmethoxycarbonyl-3-chloro-alanine benzyl ester | 吉尔生化（上海）有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-112479933-A | Preparation method of N-fluorenylmethoxycarbonyl-3-chloro-alanine benzyl ester | 吉尔生化（上海）有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112479933-A | Preparation method of N-fluorenylmethoxycarbonyl-3-chloro-alanine benzyl ester | 吉尔生化（上海）有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-109627185-A | A kind of preparation method of N- fluorenylmethyloxycarbonyl-O- caprylyl-serine/threonine | 吉尔生化（上海）有限公司 | 2019-04-16 | — | — | CN | disclosed |