Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549268 | 1.00 | PNMT (0.43) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL9737341 | 0.91 | CTSK (0.39) | PNMTNPC1RAB9AACEEPHX1 | |
| SCHEMBL9737322 | 0.91 | CTSK (0.39) | PNMTNPC1RAB9AACEEPHX1 | |
| SCHEMBL27873081 | 0.90 | PNMT (0.42) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL1420538 | 0.90 | CASP1 (0.46) | PNMTCASP1 | |
| SCHEMBL30904667 | 0.90 | CASP1 (0.46) | PNMTCASP1 | |
| SCHEMBL30146700 | 0.90 | PNMT (0.42) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL30122530 | 0.90 | CASP1 (0.46) | PNMTCASP1 | |
| SCHEMBL18689470 | 0.90 | PNMT (0.42) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL9331302 | 0.90 | CASP1 (0.46) | PNMTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473249-A1 | CROSSLINKABLE DENDRIMERS | Wayne State University (US) | 2019-04-24 | — | — | EP | claimed |
| CN-107176975-A | A kind of method of synthesis in solid state Gonadorelin | 丹东中科润华生物科技有限公司 | 2017-09-19 | — | — | CN | claimed |
| US-20170028075-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | Ashvattha Therapeutics, Inc. | 2017-02-02 | — | — | US | claimed |
| US-9526794-B2 | Injectable dendrimer hydrogel nanoparticles | WAYNE STATE UNIVERSITY (US) | 2016-12-27 | — | — | US | claimed |
| US-20130136697-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | NATIONAL INSTITUTES OF HEALTH (US) | 2013-05-30 | — | — | US | claimed |
| EP-2552458-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | Wayne State University (US) | 2013-02-06 | — | — | EP | claimed |
| WO-2011123591-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | WAYNE STATE UNIVERSITY (US) | 2011-10-06 | — | — | WO | claimed |
| CN-101224306-B | Folic acid-polypeptide compound-mediated targeting anti-tumor prodrug and preparing method thereof | UNIV SUN YAT SEN | 2011-04-20 | — | — | CN | claimed |
| CN-100590068-C | Method for preparing primary amine carbon nano tube | UNIV TONGJI | 2010-02-17 | — | — | CN | claimed |
| US-11446238-B2 | Injectable dendrimer hydrogel nanoparticles | WAYNE STATE UNIVERSITY (US) | 2022-09-20 | — | — | US | disclosed |
| CN-113072620-B | PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof | 南通大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113416232-B | Polypeptide compounds with PD-1 receptor as target spot, preparation method and application thereof | 南通大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-114437714-A | Circular polarization luminescent material based on enantioselective co-assembly and application thereof | 中国科学院化学研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-113416232-A | Polypeptide compounds with PD-1 receptor as target spot, preparation method and application thereof | 南通大学 | 2021-09-21 | — | — | CN | disclosed |
| WO-2011123591-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | WAYNE STATE UNIVERSITY (US) | 2011-10-06 | — | — | WO | disclosed |
| CN-100590068-C | Method for preparing primary amine carbon nano tube | UNIV TONGJI | 2010-02-17 | — | — | CN | disclosed |
| CN-101177259-A | Method for preparing primary amine carbon nano tube | UNIV TONGJI (CN) | 2008-05-14 | — | — | CN | disclosed |
| EP-0549727-A1 | CARBOXYLIC ACID ESTERS OF RAPAMYCIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5130307-A | Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| WO-1992005179-A1 | CARBOXYLIC ACID ESTERS OF RAPAMYCIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170028075-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | PAM, UACA, FLT1 | PNMT 1693/4885TGM2 537/4885NPC1 4774/4885 |
| US-20130136697-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | UACA, PAM, JAK3 | PNMT 2576/4885TGM2 821/4885NPC1 4700/4885 |
| US-11446238-B2 | Injectable dendrimer hydrogel nanoparticles | PAM, UACA, FLT1 | PNMT 1693/4885TGM2 537/4885NPC1 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.