SCHEMBL10692906

SCHEMBL10692906

NS(=O)(=O)c1ccc(Cc2ccccc2O)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.61
CA1 P00915 16/20 0.61
CA9 Q16790 13/20 0.61
CA12 O43570 12/20 0.61
KEAP1 Q14145 1/20 0.61
CA14 Q9ULX7 6/20 0.59
CA4 P22748 3/20 0.53
CA6 P23280 3/20 0.53
CA5A P35218 3/20 0.53
CA7 P43166 3/20 0.53
CA5B Q9Y2D0 3/20 0.53
HSPA5 P11021 1/20 0.52
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2578944 0.84 KEAP1 (0.59) CA2CA1CA9CA12KEAP1
SCHEMBL30616875 0.82 KEAP1 (0.86) CA2CA9CA12KEAP1HSPA5
SCHEMBL9776607 0.82 KEAP1 (0.86) CA2CA9CA12KEAP1HSPA5
SCHEMBL5677878 0.80 CA2 (0.72) CA2CA1CA9CA12CA14
SCHEMBL10690610 0.79 CA2 (0.89) CA2CA1CA9CA12CA14
SCHEMBL309694 0.78 CA2 (0.73) CA2CA1CA9CA12CA14
SCHEMBL10622742 0.77 KEAP1 (0.70) KEAP1HSPA5
SCHEMBL8925742 0.77 KEAP1 (0.76) CA2CA1CA9CA12KEAP1
SCHEMBL68653 0.77 KEAP1 (1.00) KEAP1HSPA5MAPT
SCHEMBL29506902 0.77 KEAP1 (1.00) KEAP1HSPA5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed