SCHEMBL2829145

SCHEMBL2829145

Nc1nc(C(=O)c2c[nH]c(N)n2)c[nH]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
GDA Q9Y2T3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380631 0.86
SCHEMBL614787 0.84
SCHEMBL8077550 0.82
SCHEMBL11030866 0.80 AKR1B1 (0.30)
SCHEMBL10860606 0.74 L3MBTL1 (0.38)
Hydrochloric Acid SCHEMBL10858713 0.73 L3MBTL1 (0.38)
SCHEMBL1407854 0.73 CYP1A2 (0.51) LMNA
SCHEMBL31324235 0.73 NR4A2 (0.34)
SCHEMBL4636005 0.73 GABRA1 (0.37)
SCHEMBL1040746 0.71 NOTUM (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022072699-A1 SILK FIBROIN USED ON WOOL TO IMPROVE ANTI-SHRINKAGE PERFORMANCE EVOLVED BY NATURE, INC. (US) 2022-04-07 WO disclosed
WO-2015036000-A1 ENZYME SUBSTRATE Københavns Universitet (DK) 2015-03-19 WO disclosed
WO-2012175092-A1 POLYMER ELECTROLYTE MEMBRANE TEKNOLOGISK INSTITUT (DK) 2012-12-27 WO disclosed
WO-2010069312-A1 METHOD OF COATING A HEARING AID COMPONENT AND A HEARING AID WIDEX A/S (DK) 2010-06-24 WO disclosed
EP-1879873-A1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK Holdings Co., Ltd. (KR) 2008-01-23 EP disclosed
WO-2006112685-A1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK HOLDINGS CO., LTD. (KR) 2006-10-26 WO disclosed