SCHEMBL614787

SCHEMBL614787

Nc1nc(C(=O)O)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2829145 0.84 LMNA (0.32)
SCHEMBL380631 0.84
SCHEMBL11030866 0.83 AKR1B1 (0.30)
SCHEMBL8077550 0.80
SCHEMBL31324235 0.75 NR4A2 (0.34)
SCHEMBL163471 0.74
SCHEMBL20582681 0.74
SCHEMBL87944 0.74 ALOX15 (0.41)
SCHEMBL4030743 0.74 LMNA (0.38)
SCHEMBL3105669 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118703022-A High-flame-retardance sheet molding compound and preparation method thereof 富仕德新材料制造(淮安)有限公司 2024-09-27 CN claimed
WO-2023072104-A1 METAL-ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR 广东美的白色家电技术创新中心有限公司 2023-05-04 WO claimed
CN-114044913-A Metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2022-02-15 CN claimed
CN-109337071-B Additive applied to polyimide purification and electronic grade polyimide product 深圳市大分子科技有限公司 2021-12-14 CN claimed
US-20160158320-A1 DEVICE AND METHOD FOR THE DELIVERY OF DRUGS FOR THE TREATMENT OF POSTERIOR SEGMENT DISEASE DIRECT CONTACT LLC (US) 2016-06-09 US claimed
EP-3325513-B1 ANTI-PD-L1 ANTIBODIES AND USES THEREOF I MAB BIOPHARMA CO LTD (CN) 2026-05-20 EP disclosed
US-20260130893-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-05-14 US disclosed
EP-4735453-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-05-06 EP disclosed
EP-4735445-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-05-06 EP disclosed
WO-2026089992-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2026-04-30 WO disclosed
US-20260116987-A1 ANTIBODIES AND FUSION PROTEINS THAT BIND TO CCR8 AND USES THEREOF GILEAD SCIENCES INC (US) 2026-04-30 US disclosed
US-20260098098-A1 ANTIBODIES AND FUSION PROTEINS THAT BIND TO CCR8 AND USES THEREOF GILEAD SCIENCES INC (US) 2026-04-09 US disclosed
US-6927290-B2 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-08-09 US disclosed
EP-1160236-B1 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL CO (JP) 2005-05-25 EP disclosed
US-20050074497-A1 Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases DIRECTCONTACT LLC 2005-04-07 US disclosed
US-20040210059-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-6753431-B2 REACTING A CARBAMATE DERIVATIVE WITH CARBOXYLIC AND HALOFORMIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-06-22 US disclosed
US-20020032346-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL CO., LTD. 2002-03-14 US disclosed
EP-1160236-A2 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-05 EP disclosed
WO-1990014009-A1 THERAPEUTIC APPLICATION OF AN ANTI-INVASION COMPOUND THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1990-11-29 WO disclosed