Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447353 | 0.80 | L3MBTL1 (0.47) | HRH3ALDH1A1LMNATAAR1ALOX15 | |
| SCHEMBL19590951 | 0.75 | SMN1; SMN2 (0.48) | PDE10AADAMTS5ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2749419 | 0.75 | L3MBTL1 (0.44) | HRH3ALDH1A1LMNATAAR1ALOX15 | |
| SCHEMBL14459786 | 0.75 | HDAC1 (0.52) | ALDH1A1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL4174781 | 0.74 | HDAC1 (0.45) | ALDH1A1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4938201 | 0.73 | L3MBTL1 (0.57) | HRH3ALDH1A1LMNATAAR1ALOX15 | |
| SCHEMBL24803900 | 0.73 | GCK (0.56) | PDE10AGCKADORA2AADORA1ALDH1A1 | |
| SCHEMBL764538 | 0.72 | GRM5 (0.49) | HRH3ALDH1A1LMNATAAR1ALOX15 | |
| SCHEMBL22334910 | 0.71 | RAB9A (0.55) | PDE10AGCKHRH3ALDH1A1LMNA | |
| SCHEMBL29830938 | 0.71 | L3MBTL1 (0.59) | HRH3ALDH1A1LMNATAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |