Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710161 | 0.85 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1VCAM1 | |
| SCHEMBL13241715 | 0.83 | HSD17B10 (0.62) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL863249 | 0.83 | HSD17B10 (0.62) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8262558 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL842908 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1663175 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2182437 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29906404 | 0.81 | HSD17B10 (0.60) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10748239 | 0.81 | HSD17B10 (0.55) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL34471822 | 0.81 | HSD17B10 (0.55) | HSD17B10LMNASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404231-B2 | Method for preparing trifluoromethyl aromatic compound | JINGDEZHEN FUSHINE LIFE TECHNOLOGY CO., LTD. (CN) | 2025-09-02 | — | — | US | disclosed |
| US-20250257028-A1 | Method for Preparing Trifluoromethyl Aromatic Compound | JINGDEZHEN FUSHINE LIFE TECHNOLOGY CO., LTD. (CN) | 2025-08-14 | — | — | US | disclosed |
| CN-117964490-B | Preparation method of trifluoromethyl aromatic compound | 景德镇富祥生命科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-117964490-A | Preparation method of trifluoromethyl aromatic compound | 景德镇富祥生命科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-109748885-A | A kind of preparation method of Ceritinib intermediate and Ceritinib | 新发药业有限公司 | 2019-05-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257028-A1 | Method for Preparing Trifluoromethyl Aromatic Compound | PAH, KCNH3, RCC1 | HSD17B10 3239/4885LMNA 946/4885SMN1; SMN2 3200/4885 |
| US-12404231-B2 | Method for preparing trifluoromethyl aromatic compound | PAH, KCNH3, RCC1 | HSD17B10 3239/4885LMNA 946/4885SMN1; SMN2 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.