SCHEMBL28291646

SCHEMBL28291646

CC=CC=COC(=O)NCCC

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.38
ACHE P22303 8/20 0.37
EPHX1 P07099 2/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
ATM Q13315 1/20 0.34
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514362 0.79
SCHEMBL19944959 0.75 CHRM2 (0.33) EPHX1CHRNB2CHRNA4
SCHEMBL3686778 0.74
SCHEMBL1415870 0.74 EPHX1 (0.45) BCHEACHEEPHX1CHRNB2CHRNB4
SCHEMBL1415805 0.72 EPHX1 (0.44) BCHEACHEEPHX1CHRNB2CHRNB4
SCHEMBL27468779 0.70
SCHEMBL515070 0.69
SCHEMBL7790364 0.68 ACHE (0.59) BCHEACHEEPHX1
SCHEMBL1416357 0.68 EPHX1 (0.53) ACHEEPHX1
Hydrochloric Acid SCHEMBL22345320 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666159-A A kind of method of energy-absorbing and application thereof 翁秋梅 2019-04-23 CN disclosed
CN-109666093-A A kind of dynamic aggregation object with hybrid cross-linked network structure 翁秋梅 2019-04-23 CN disclosed