Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458227 | 0.75 | GSK3B (0.35) | IDH1GSK3BADRA1ATRIM24TRIM33 | |
| SCHEMBL16595227 | 0.74 | DRD2 (0.41) | IDH1ALDH1A1DRD2DRD3TRIM24 | |
| SCHEMBL24096699 | 0.74 | PLAU (0.37) | IDH1GSK3BADRA1AHTR2AHTR2C | |
| SCHEMBL20153297 | 0.74 | GSK3B (0.37) | IDH1GSK3BALDH1A1ADRA1AHTR2A | |
| SCHEMBL2298946 | 0.74 | MTNR1A (0.44) | — | |
| Hydrochloric Acid SCHEMBL31277891 | 0.72 | PLAU (0.36) | IDH1ADRA1AHTR2AHTR2CHTR2B | |
| SCHEMBL30585791 | 0.72 | IDH1 (0.43) | IDH1 | |
| SCHEMBL6013246 | 0.72 | IDH1 (0.43) | IDH1 | |
| SCHEMBL4597831 | 0.71 | DRD2 (0.52) | IDH1DRD2DRD3 | |
| SCHEMBL28149742 | 0.71 | IDH1 (0.42) | IDH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745321-A | Pharmaceutical composition comprising FGFR4 inhibitor | 上海翰森生物医药科技有限公司 | 2019-05-14 | — | — | CN | disclosed |