Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291731 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1CETPCYP1A2 | |
| SCHEMBL28872854 | 0.85 | CETP (0.47) | LMNASMN1; SMN2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL28291870 | 0.84 | LMNA (0.52) | LMNAHSD11B1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL4491943 | 0.84 | CETP (0.45) | LMNASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28293342 | 0.82 | LMNA (0.47) | LMNAHSD11B1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL22092656 | 0.81 | LMNA (0.44) | LMNAHSD11B1SMN1; SMN2MEN1GAA | |
| SCHEMBL28293345 | 0.81 | TSHR (0.43) | SMN1; SMN2L3MBTL1MEN1KMT2ACETP | |
| SCHEMBL5929556 | 0.81 | L3MBTL1 (0.52) | LMNASMN1; SMN2L3MBTL1ALDH1A1CETP | |
| SCHEMBL6570728 | 0.81 | L3MBTL1 (0.52) | LMNASMN1; SMN2L3MBTL1ALDH1A1CETP | |
| SCHEMBL20143336 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1CETPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608390-B | Synthesis method of chiral quaternary carbon pyridine beta-hydroxy ester compound | 温州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608390-A | A kind of synthetic method of chirality quaternary carbon pyridines β hydroxyl esters compound | 温州大学 | 2019-04-12 | — | — | CN | disclosed |