Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291726 | 0.87 | SMN1; SMN2 (0.44) | LMNACYP1A2SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL28291723 | 0.84 | LMNA (0.50) | LMNAHSD11B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5929588 | 0.82 | L3MBTL1 (0.47) | LMNACYP1A2CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL28293342 | 0.81 | LMNA (0.47) | LMNAHSD11B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8341741 | 0.79 | SMN1; SMN2 (0.59) | LMNACYP1A2SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL6996539 | 0.78 | SMN1; SMN2 (0.48) | LMNAHSD11B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19125845 | 0.74 | LMNA (0.49) | LMNAHSD11B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5874327 | 0.74 | LMNA (0.43) | LMNAHSD11B1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25512278 | 0.74 | LMNA (0.44) | LMNAHSD11B1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL28403527 | 0.73 | LMNA (0.47) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608390-B | Synthesis method of chiral quaternary carbon pyridine beta-hydroxy ester compound | 温州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608390-A | A kind of synthetic method of chirality quaternary carbon pyridines β hydroxyl esters compound | 温州大学 | 2019-04-12 | — | — | CN | disclosed |