Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 17/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225826 | 0.87 | SLC6A2 (0.49) | GPR6HTR1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL16818301 | 0.85 | SLC6A2 (0.48) | GPR6HTR1ASLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28101025 | 0.84 | HTR2C (0.46) | SLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28072762 | 0.83 | NMT1 (0.40) | GPR6HTR1ASLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL27805796 | 0.77 | UTS2R (0.43) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL23686797 | 0.76 | SLC6A9 (0.47) | GPR6 | |
| SCHEMBL18855637 | 0.76 | SLC6A9 (0.47) | GPR6 | |
| Tert-Butyl Formate SCHEMBL28221270 | 0.75 | HTR1A (0.39) | HTR1ASLC6A2SLC6A3CTSSCTSK | |
| SCHEMBL17008795 | 0.75 | GPR6 (0.47) | GPR6 | |
| SCHEMBL23842656 | 0.75 | SLC6A4 (0.48) | HTR1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103421-B | The pyrazine regulator of GPR6 | 武田药品工业株式会社 | 2019-04-09 | — | — | CN | disclosed |