SCHEMBL28291933

SCHEMBL28291933

Cc1cccc(Nc2ccccc2CCO)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
MAPT P10636 4/20 0.48
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP6 P55212 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
EGFR P00533 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
PTGS2 P35354 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTT P42858 1/20 0.43
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1922073 0.83 NPSR1 (0.72) NPSR1MAPTALDH1A1EGFRPTGS2
SCHEMBL28290543 0.82 MAPT (0.51) NPSR1MAPTHPGDKDM4EALDH1A1
SCHEMBL4726148 0.82 AURKA (0.65) MAPK1EGFR
SCHEMBL28549525 0.81 FABP4 (0.47) NPSR1MAPTHPGDKDM4EALDH1A1
SCHEMBL7166092 0.79 PTGS2 (0.62) NPSR1MAPTGAAPTGS2CYP2C9
SCHEMBL27597738 0.78 MAPK14 (0.42) MAPTHPGDKDM4EALDH1A1GAA
SCHEMBL1623708 0.76 SLC6A4 (0.66) MAPTKDM4EALDH1A1GAAHSD17B10
SCHEMBL1626521 0.75 TRPV1 (0.50) MAPTKDM4EALDH1A1GAAL3MBTL1
SCHEMBL14952480 0.75 NPSR1 (0.60) NPSR1MAPTALDH1A1EGFRPTGS2
SCHEMBL28291986 0.75 PTGS2 (0.45) MAPTHPGDKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109706194-B Method for synthesizing phenethyl alcohol beta-amino alcohol derivatives on line based on mobile chemical enzymatic ammonolysis reaction 浙江工业大学 2021-04-06 CN disclosed
CN-109706194-A A method of phenylethanol beta-alkamine derivative is synthesized online based on chemical enzymatic aminolysis reaction is flowed 浙江工业大学 2019-05-03 CN disclosed