Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549525 | 0.85 | FABP4 (0.47) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL29110685 | 0.83 | MAPT (0.55) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL31310616 | 0.83 | MAPKAPK2 (0.48) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL5786086 | 0.83 | PTGS2 (0.41) | MAPTTDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL31310568 | 0.82 | POLB (0.41) | MAPTNPC1RAB9AHPGDKDM4E | |
| SCHEMBL28291933 | 0.82 | NPSR1 (0.51) | MAPTGAANPC1RAB9AHPGD | |
| SCHEMBL11636131 | 0.81 | MAPT (0.50) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL1713014 | 0.81 | MAPT (0.72) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL30146895 | 0.80 | NPC1 (0.59) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL887264 | 0.80 | NPC1 (0.59) | MAPTGAATDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118850-A | Method for preparing amino phenethyl alcohol compound by reforming indole compound structure | 中国科学院兰州化学物理研究所 | 2024-12-13 | — | — | CN | disclosed |
| CN-109706194-B | Method for synthesizing phenethyl alcohol beta-amino alcohol derivatives on line based on mobile chemical enzymatic ammonolysis reaction | 浙江工业大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109706194-A | A method of phenylethanol beta-alkamine derivative is synthesized online based on chemical enzymatic aminolysis reaction is flowed | 浙江工业大学 | 2019-05-03 | — | — | CN | disclosed |