SCHEMBL28291959

SCHEMBL28291959

C=C(N)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.35
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28377582 0.83 MGLL (0.36) MGLL
SCHEMBL865136 0.82 MGLL (0.40) MGLLKMT2AATM
SCHEMBL28964134 0.81 MGLL (0.36) MGLLKMT2AATM
SCHEMBL73278 0.79 KMT2A (0.47) MGLLKMT2AATM
SCHEMBL118685 0.78 PARL (0.41) MGLLKMT2AATM
SCHEMBL699757 0.78 MGLL (0.36) MGLL
SCHEMBL17550003 0.76 KMT2A (0.38) MGLLKMT2AATM
SCHEMBL19542237 0.76 MGLL (0.36) MGLLKMT2AATM
SCHEMBL12415420 0.76 KMT2A (0.35) MGLLKMT2AATM
SCHEMBL12336668 0.75 PARL (0.33) MGLLKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608379-A A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method 苏州昊帆生物股份有限公司 2019-04-12 CN claimed