Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.39 |
| ▸ | PDE6A | P16499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115635 | 0.74 | CYP1A2 (0.47) | FAAHNPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL2066324 | 0.73 | FFAR2 (0.40) | RAB9ATDP1ALDH1A1MAPTMAPK1 | |
| Aminothiazole SCHEMBL28843713 | 0.72 | ALDH1A1 (0.49) | NPC1RAB9ATDP1ALDH1A1CYP1A2 | |
| SCHEMBL28291973 | 0.71 | ALDH1A1 (0.48) | FAAHNPC1RAB9AALDH1A1PKM | |
| SCHEMBL27662756 | 0.71 | CYP1A1 (0.46) | ALDH1A1CYP1A2CYP1A1CYP1B1KMT2A | |
| SCHEMBL28843776 | 0.70 | TAAR1 (0.50) | ALDH1A1CYP1A2MAPTFYN | |
| SCHEMBL109195 | 0.70 | TAAR1 (0.64) | ALDH1A1CYP1A2MAPT | |
| SCHEMBL6958536 | 0.69 | FAAH (0.55) | FAAHNPC1RAB9ARXFP1TDP1 | |
| SCHEMBL108109 | 0.68 | TAAR1 (0.62) | ALDH1A1CYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL11325724 | 0.68 | NPC1 (0.62) | FAAHNPC1RAB9ARXFP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699752-B | Application of the 5- piperonyl -2- pridylamino thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | claimed |
| CN-106699752-B | Application of the 5- piperonyl -2- pridylamino thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106699752-B | Application of the 5- piperonyl -2- pridylamino thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106699752-B | Application of the 5- piperonyl -2- pridylamino thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |