Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886467 | 0.91 | CNR1 (0.55) | ALDH1A1TSHRATMNPSR1CNR1 | |
| SCHEMBL7190397 | 0.89 | GPR84 (0.52) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28051878 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28051728 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28051687 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL5012393 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28825910 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28051701 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| Fluorene SCHEMBL28292223 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 | |
| SCHEMBL28051879 | 0.87 | HTR2A (0.56) | ALDH1A1TSHRATMNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330508-B | One kind 3 is monosubstituted or 3,6 2 replace fluorene derivative and its preparation method and application | 亚培烯科技（杭州）有限公司 | 2019-04-19 | — | — | CN | disclosed |