SCHEMBL4886467

SCHEMBL4886467

CCCc1ccc2c(c1)-c1cc(CCC)ccc1C2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.55
CNR2 P34972 1/20 0.55
ALOX5 P09917 2/20 0.43
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
PDK2 Q15119 1/20 0.39
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
HTR2C P28335 3/20 0.37
HTR2B P41595 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HTR2A P28223 2/20 0.36
DRD2 P14416 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
CTSD P07339 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292217 0.91 ALDH1A1 (0.49) CNR1CNR2PDK2GABRA1GABRB2
SCHEMBL4896384 0.88 SKP2 (0.47) CNR1CNR2LPLLIPGHTR2C
SCHEMBL4900256 0.87 CNR1 (0.50) CNR1CNR2ALOX5LPLLIPG
SCHEMBL4894434 0.86 HTR2A (0.49) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL4895890 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL4896260 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL4890264 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL28825911 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL4897218 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A
SCHEMBL28051680 0.84 SLC6A2 (0.51) LPLLIPGHTR2CALDH1A1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348330-A 3 mono-substituted or 3,6 bis-substituted fluorenyl metalloscene and preparation method and application thereof SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD 2016-02-24 CN disclosed
CN-105330508-A 3-monosubstituted or 3,6-disubstituted fluorene derivative and preparing method and application thereof SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD 2016-02-17 CN disclosed
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 CNR1 2078/4885CNR2 2221/4885ALOX5 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.